Bufferin A
バファリンA
Designated Class 2 — Use with special caution
Drug Type
Analgesic and antipyretic (aspirin)
Form
Tablets
Indication
Relief of headache, menstrual pain, joint pain, neuralgia, back pain, muscle pain, shoulder stiffness pain, sore throat, toothache, post-extraction pain, bruising pain, sprain pain, fracture pain, traumatic pain, and earache; and reduction of fever and chills
Warnings & Precautions
Contains no pyrazolones.
Active Ingredients (per 2 tablets)
• Aspirin (acetylsalicylic acid) 660mg • Synthetic hydrotalcite (Dibuffer HT) 200mg
Inactive Ingredients
Cornstarch, magnesium stearate, hypromellose, titanium oxide, macrogol, Blue No. 1
Instructions for Use
- ✓Take with lukewarm or cold water. Avoid taking on an empty stomach. Allow at least 6 hours between doses.
| Age | Dose per use | Times per day |
|---|---|---|
| Adults (15 years and older) | 2 tablets | Up to 2 times daily |
| Under 15 years | Do not use | — |
- ✕Do not take if you have had an allergic reaction to this product or any of its ingredients.
- ✕Do not take if you have experienced an asthma attack triggered by this product, other analgesics or antipyretics, or cold medicines.
- ✕Do not take if you are under 15 years of age.
- ✕Do not take if you are pregnant and expecting to give birth within 12 weeks.
- ✕Do not use with other analgesics/antipyretics, cold medicines, or sedatives.
- ✕Do not drink alcohol before or after taking this medication.
- ✕Do not take for an extended period.
- ✓If any of the following occur after taking, stop immediately and consult a physician, dentist, pharmacist, or registered salesperson: skin rash, redness, itchiness, or bruising; nausea, vomiting, loss of appetite, heartburn, heaviness in the stomach, gastrointestinal bleeding, abdominal pain, diarrhea, or bloody stool; dizziness; or nosebleed, bleeding from the gums, prolonged bleeding, fever, sore throat, back pain, or excessive drop in body temperature.
- ✓Seek immediate medical attention if you experience itchy skin, hives, hoarseness, sneezing, itchy throat, difficulty breathing, heart palpitations, or feeling faint (possible anaphylactic shock); severe fever, bloodshot eyes, eye mucus, lip sores, sore throat, or widespread rash or skin redness (possible Stevens-Johnson syndrome or toxic epidermal necrolysis); chest pain, shortness of breath, chest pressure, jaw pain, pain in the left arm, chills, dizziness, sweating, fever, loss of consciousness, swelling of the lips, itchiness, hives, rash, itchy throat, or heart palpitations (possible acute coronary syndrome associated with allergic reaction); fever, itchiness, rash, jaundice, brown urine, overall lethargy, or loss of appetite (possible liver damage); wheezing or difficulty breathing (possible asthma); or bruising, nosebleed, bleeding from the gums, fever, pale skin or mucous membranes, fatigue, heart palpitations, shortness of breath, nausea, dizziness, or bloody urine (possible aplastic anemia).
- ⚠Consult a physician, dentist, pharmacist, or registered salesperson before use if you: are currently receiving medical or dental treatment; are pregnant or may be pregnant; are nursing; are elderly; have had an allergic reaction to any drug; or have been diagnosed with heart disease, kidney disease, liver disease, or stomach or duodenal ulcers.
- ✓Seek immediate medical attention if any of the following serious symptoms appear:
- • Shock (anaphylaxis): Itching of skin, hives, hoarseness, sneezing, itchy throat, difficulty breathing, palpitations, or clouding of consciousness immediately after use.
- • Stevens-Johnson syndrome / toxic epidermal necrolysis: High fever, redness of eyes, eye discharge, sores on lips, sore throat, or widespread rash or redness on skin that persists or rapidly worsens.
- • Allergy-related acute coronary syndrome: Squeezing chest pain, difficulty breathing, heavy pressure on the chest, jaw pain, left arm pain, chills, dizziness, sweating, fever, loss of consciousness, swelling around the lips, itching, hives, rash, itchy throat, or palpitations.
- • Liver disorder: Fever, itching, rash, jaundice (yellowing of the skin or whites of the eyes), dark urine, general fatigue, or loss of appetite.
- • Asthma: Wheezing or whistling breath sounds, or difficulty breathing.
- • Aplastic anemia: Bruising, nosebleed, bleeding gums, fever, pale skin or mucous membranes, fatigue, palpitations, shortness of breath, feeling faint, or blood in urine.
- ✓Strictly follow the prescribed dosage.
- ✓When removing the tablet from the PTP sheet, press the convex side firmly to break the foil on the back. Do not swallow the PTP sheet.
- ✓If symptoms do not improve after 5 to 6 doses, stop use and consult a physician, dentist, pharmacist, or registered salesperson.
Sources & Documents
- Japanese product page
- English PDF
- Japanese PDF
- Last verified: May 23, 2026
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For informational purposes only. Always consult a doctor or pharmacist before taking any medication.